Sex-Linked Inheritance

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• Most sex-linked conditions are on x chromosomes.

  • With X-linked, they have two xs, so they can either pass one on, or not.
  • With Y-linked, they can only pass the Y to a boy. So that mutated Y chromosome will pass down to every boy.

• Males aren't carriers with x-linked, because they either have the allele in the chromosome, or not.

• Females can be carriers, because they have an extra x chromosome for that allele.

• Ex:

  • Colorblindness
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• X-linked Dominant Inheritance

• X-linked Recessive Inheritance

• How to determine between x-linked and autosomal disorders

  • Males cannot pass down an x-linked disorder to a son, because the dad did not pass down an X to his son.

• How to determine between a dominant or recessive disorder